Table 4 Clinical characteristics of patients with MS and the HLA-DRB1*04:05 allele

Number of males/females (ratio)

27/65 (1:2.4)

25/55 (1:2.2)

NS

Age (years)^a

41 (34–49.5)

36 (28–49)

NS

Age at onset (years)^a

27 (21–34)

25 (20–36.8)

NS

SPMS (%)

19/92 (20.7)

7/78 (9.0)

0.035

Disease duration (years)^a

10 (6–17)

7.5 (4–14.8)

NS

EDSS^a

2.0 (1.0–3.5)

2.0 (1.0–3.0)

NS

MSSS^a

1.97 (0.56–5.63)

2.28 (1.04–4.97)

NS

ARR^a

0.40 (0.25–0.71)

0.37 (0.17–0.71)

NS

Barkhof criteria (%)

69/92 (75.0 %)

44/78 (56.4 %)

0.0105

Positive OB and/or increased IgG index (%)

41/69 (59.4 %)

17/60 (28.3 %)

0.0004