| Northern patients (n = 92) | Southern patients (n = 80) | p value |
---|---|---|---|
Number of males/females (ratio) | 27/65 (1:2.4) | 25/55 (1:2.2) | NS |
Age (years)a | 41 (34–49.5) | 36 (28–49) | NS |
Age at onset (years)a | 27 (21–34) | 25 (20–36.8) | NS |
SPMS (%) | 19/92 (20.7) | 7/78 (9.0) | 0.035 |
Disease duration (years)a | 10 (6–17) | 7.5 (4–14.8) | NS |
EDSSa | 2.0 (1.0–3.5) | 2.0 (1.0–3.0) | NS |
MSSSa | 1.97 (0.56–5.63) | 2.28 (1.04–4.97) | NS |
ARRa | 0.40 (0.25–0.71) | 0.37 (0.17–0.71) | NS |
Barkhof criteria (%) | 69/92 (75.0Â %) | 44/78 (56.4Â %) | 0.0105 |
Positive OB and/or increased IgG index (%) | 41/69 (59.4Â %) | 17/60 (28.3Â %) | 0.0004 |