Fig. 4From: Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain modelsEffects of bullatine A (a, b) and guan-fu base A (c) administered intrathecally on mechanical allodynia in neuropathic rats. Neuropathic pain was induced by tight ligation of L5/L6 spinal nerves. b Dose–response analysis of bullatine A on % maximum possible effect (% MPE) at 1 h after injection was best projected by the non-linear least-squares method. The data are presented as means ± SEM (n = 6 in each group)Back to article page