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Fig. 11 | Journal of Neuroinflammation

Fig. 11

From: 1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype

Fig. 11

Graphical summary of findings obtained during the present study. LPA treatment induces a unique pro-inflammatory M1-like signature in BV-2 and PMM that is completely or partially reversed by pre-treatment with the LPA5 inhibitor TCLPA5. Data of the present study provide functional evidence for the role of LPA5 as member of the microglia sensome

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