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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway

Fig. 3

NRG-1 suppresses TNF-α and IL-6 concentrations in LPS-stimulated N9 microglia cells. N9 microglia cells were pre-treated with NRG-1 (100 ng/ml) for 24 h with or without LPS stimulation (10 μg/ml) for the indicated time points. Supernatants were collected, and TNF-α (a) and IL-6 (b) levels were determined by Luminex. Results are expressed as the mean +/− SD. Asterisk denotes a significant difference compared to cells treated with only LPS (p < 0.05)

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