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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms

Fig. 3

Gly administration blocked T lymphocyte infiltration in the ischemia brain. Mononuclear leukocytes were extracted from ischemic brains 3 days after stroke, and the absolute numbers of lymphocyte subsets were analyzed by FACS. Contralateral hemisphere was collected as control. The drug was injected immediately and 3.5 h after suture removal. a Gating strategies for identifying CD4 and CD8 T cells. b Bar graphs for statistical results of T lymphocytes and T cell subsets. T cells, CD4, and CD8 cells were assessed. n = 7 to 12/each group. *P < 0.05 between the two indicated groups

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Journal of Neuroinflammation

ISSN: 1742-2094