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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy

Fig. 10

Infliximab normalizes extracellular GABA in the cerebellum of PCS rats. Control (sham) and PCS rats treated with vehicle or infliximab (inflix) were subjected to in vivo microdialysis in the cerebellum. Extracellular GABA was measured by HPLC in the eight initial samples of each rat. Values are the mean ± SEM of 12 sham rats treated with vehicle and 15 sham rats treated with infliximab; and 13 PCS rats treated with vehicle and 12 PCS rats treated with infliximab. Values significantly different from control are indicated by asterisks and from PCS rats by a. * p < 0.05; ** p < 0.01; a p < 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094