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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy

Fig. 2

Infliximab reduces microglial activation in the white matter of the cerebellum of PCS rats. Immunohistochemistry was performed as indicated in the “Methods” section using antibody against Iba-1. Representative low (×20; a) and high (×56; b) magnification images are shown. Perimeter (c), area (d), and ratio area/perimeter (e) of microglial cells were quantified in the white matter of the cerebellum. Values are the mean ± SEM of 4 rats per group. Values significantly different from controls are indicated by asterisks and from PCS rats by a. **p < 0.01; ***p < =0.005; aaa p < 0.005. Scale bar low magnification (a) = 100 μm; scale bar high magnification = 50 μm

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Journal of Neuroinflammation

ISSN: 1742-2094