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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy

Fig. 6

Infliximab reduces the number of IL-1β positive cells and the content of IL-b in white matter of the cerebellum of PCS rats. Immunohistochemistry was performed using antibody against IL-1β. Representative low (×20; a) and high (×40; b) magnification images are shown. The number of IL-1β positive cells was quantified (c) in the white matter of the cerebellum. Values are the mean ± SEM of 4 rats per group. The content of IL-1β in homogenates of the whole the cerebellum was also analyzed by western blot (d). Representative images are shown. Values significantly different from controls are indicated by asterisks and from PCS rats by a. *p < =0.05; ***p < =0.005; a p < 0.05. Scale bar low magnification (a) = 100 μm; scale bar high magnification = 50 μm

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Journal of Neuroinflammation

ISSN: 1742-2094