Fig. 2
From: Loss of Schwann cell plasticity in chronic inflammatory demyelinating polyneuropathy (CIDP)
a Longitudinal sections of nerve sections two weeks after CFP-labeled Schwann cell grafting. 1: control nerve after staining with S100. 2: nerve section with Schwann cells graft after S100 staining. 3: nerve sections show spotty distribution of GFP-labeled Schwann cells. 4: staining of GFP-labeled Schwann cells with an antibody against GFP (bar = 20 μm). b Effect of transplantation of Schwann cells treated with CIDP or control sera on denervated nerve stumps. Transplantation of Schwann cells treated with CIDP sera (circles) resulted in slower and lower CMAP amplitude generation in rats compared to control (squares). c Semi-thin sections of nerves show significantly less number of regenerating axons in nerves from rats transplanted with CIDP treated Schwann cells compared to control. The graph shows quantification of all myelinated regenerated axons. n = 5 rats each group *p < 0.05 (ANOVA and independent t test) (bar = 20 μm)