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Table 4 Antibody reactivity in the SCI cohort and age- and gender-matched healthy controls

From: Antibody profiling identifies novel antigenic targets in spinal cord injury patients

Clone

Identification cohort (n = 10)

Validation cohort (n = 41)

Total cohort (n = 51)

HCc (n = 49)

Fisher’s exact test (p value)d

   

tSCIa (n = 25)

pSCIb (n = 26)

Total (n = 51)

  

UH.SCI.1

1/10 (10 %)

3/41 (7 %)

2/25 (8 %)

2/26 (8 %)

4/51 (8 %)

2/49 (4 %)

ns

UH.SCI.2

1/10 (10 %)

4/41 (10 %)

2/25 (8 %)

3/26 (12 %)

5/51 (10 %)

1/49 (2 %)

ns

UH.SCI.7

2/10 (20 %)

2/41 (5 %)

2/25 (8 %)

2/26 (8 %)

4/51 (8 %)

2/49 (4 %)

ns

UH.SCI.8

2/10 (20 %)

1/41 (2 %)

2/25 (8 %)

1/26 (4 %)

3/51 (6 %)

2/49 (4 %)

ns

UH.SCI.9

1/10 (10 %)

5/41 (12 %)

3/25 (12 %)

3/26 (12 %)

6/51 (12 %)

0/49 (0 %)

0.0134

UH.SCI.11

3/10 (30 %)

7/41 (17 %)

5/25 (20 %)

5/26 (19 %)

10/51 (20 %)

5/49 (10 %)

ns

UH.SCI.12

1/10 (10 %)

1/41 (2 %)

1/25 (4 %)

1/26 (4 %)

2/51 (4 %)

0/49 (0 %)

ns

UH.SCI.13

1/10 (10 %)

1/41 (2 %)

1/25 (4 %)

1/26 (4 %)

2/51 (4 %)

1/49 (2 %)

ns

UH.SCI.15

1/10 (10 %)

4/41 (10 %)

3/25 (12 %)

2/26 (8 %)

5/51 (10 %)

1/49 (2 %)

ns

Total cohort

7/10 (70 %)

19/41 (46 %)

13/25 (52 %)

13/26 (50 %)

26/51 (51 %)

13/49 (27 %)

0.0073

Panel of 6 targets (bold)

6/10 (60 %)

18/41 (44 %)

12/25 (48 %)

12/26 (46 %)

24/51 (47 %)

9/49 (18 %)

0.00145

  1. a tSCI traumatic spinal cord injury
  2. b pSCI pathologic spinal cord injury
  3. c HC healthy control
  4. d ns not significant