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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: In vitro evaluation of physiologically relevant concentrations of teriflunomide on activation and proliferation of primary rodent microglia

Fig. 2

Teriflunomide does not modulate morphological shaping of non-activated and activated cultured microglia. Cultured microglia were treated with teriflunomide (0.25–5 μM) for 24 h without (ae) or with 100 ng/ml LPS/50 ng/ml IFN-γ (pre-treatment: fj; co-treatment: ko). Immunofluorescence microscopy images show Iba-1+ microglia stained with DAPI as marker for cell viability (n = 4). LPS/IFN-γ-treatment (fo) induces morphological changes in comparison with non-activated cells (ae). Scale bar = 20 μm

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