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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

Fig. 1

MOG-IgG as detected by two independent cell-based assays (CBA): typical findings. a, b Binding of serum IgG from a group I patient (a) but not from a control patient (b) to live HEK293A cells transfected with human full-length MOG. c, d Binding of serum IgG from a group I patient to formalin-fixed HEK293 cells transfected with full-length MOG (c) but not to their mock-transfected counterpart (d) in a commercial CBA. Bound MOG-IgG was visualized in the live-cell assay using a Cy3-conjugated goat anti-human IgG antibody and in the fixed-cell assay by use of a fluorescein isothiocyanate (FITC)-labeled goat anti-human IgG antibody

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