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Table 2 Lack of evidence for intrathecal IgG synthesis in 17 CSF samples from 15

From: MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

Sample no.

MOG-IgG titer, serum

MOG-IgG titer, CSF

MOG-IgG titer required for AI >4

Evidence for intrathecal MOG-IgG synthesis

#1

1:10240

1:64

1:925.7

No

#2

1:2560

1:4

1:25.6

No

#3

1:320

1:2

1:2.3

No

#4

1:10240

1:16

1:152.5

No

#5

1:640

1:4

1:9

No

#6

1:2560

1:4

1:30.7

No

#7

1:10240

1:16

1:176.1

No

#8

1:2560

1:2

1:19.5

No

#9

1:320

1:2

1:3.6

No

#10

1:1280

1:2

1:9.4

No

#11

1:2560

1:4

1:25

No

#12

1:320

1:4

1:6

No

#13a

1:1280

NEG

1:17.4

No

#14

1:320

NEG

1:3.7

No

#15

1:1280

NEG

1:10.2

No

#16

1:160

NEG

1:2.1

No

#17b

1:1280

NEG

1:10.2

No

  1. MOG-IgG seropositive patients with ON and/or myelitis. NEG negative. aFollow-up to sample #1; b follow-up to sample #2