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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Brain omega-3 polyunsaturated fatty acids modulate microglia cell number and morphology in response to intracerebroventricular amyloid-β 1-40 in mice

Fig. 6

Fluoro Jade C-positive cells (±SEM) in the CA1 (a) and DG (b) regions of the hippocampus. Graphs represent counts (mean of three boxes per image) at 10 days post-icv amyloid-β 1-40. Representative images of the CA1 (c) and DG (d) of the following: from left to right: LPS-injected positive control mice, wild type mice fed safflower oil (WTSO), fat-1 transgenic mice fed safflower (fat-1), and wild type mice fed fish oil (WTFO) mice showing the FJC-positive cells (top) and Hoescht staining (a non-discriminate DNA stain). Images are enhanced for contrast and sharpness for publication. All graphs represent values at 10 days post-intracerebroventricular infusion of amyloid-β 1-40 normalized for non-surgery values ±SEM. Different letters denote significant differences (p < 0.05) as determined by one-way ANOVA with Bonferroni post hoc test. CA cornu ammonis, DG dentate gyrus, WTSO wild type mice fed safflower oil, fat-1 fat-1 mice fed safflower oil, WTFO wild type mice fed fish oil

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