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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Brain region and epilepsy-associated differences in inflammatory mediator levels in medically refractory mesial temporal lobe epilepsy

Fig. 1

a Eotaxin levels in human brain specimens. Overall, the hippocampal levels were greater than the entorhinal and temporal cortex. b Epilepsy-related eotaxin differences. Brain levels of eotaxin were greater among nonepileptic cases overall, and the nonepileptic entorhinal cortex eotaxin was greater than in the epileptic entorhinal cortex. c IP-10 levels were not significantly different between brain regions. d MCP-4 levels appeared lower in the entorhinal cortex than the other tissues. e MIP-1α and f MIP-1β levels in the human brain showed similar regional differences. In all graphs, blue = nonepileptic cases, red = epileptic cases. Data points are means of duplicate measurements; diamond graphs show the grand mean for all cases as a horizontal line, diamond center line indicates group mean, upper and lower triangles indicate the 95 % confidence intervals. Histograms show group mean ± standard error; solid lines show within epilepsy status, and dashed lines show between epilepsy status group differences. Post hoc testing: **p < 0.001; *p < 0.01; § p < 0.05, Tukey’s HSD; ¶ p < 0.01, non-parametric Wilcoxon/Kruskal-Wallis, unless otherwise noted

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