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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Adoptive transfer of M2 macrophages reduces neuropathic pain via opioid peptides

Fig. 3

Opioid peptide content and release from cultured macrophages following polarization. Intracellular content (a) and extracellular, released levels (b) of Met-enkephalin, dynorphin, and β-endorphin. Opioid peptide levels were measured by RIA (Met-enkephalin and dynorphin) or EIA (β-endorphin), ~18 h after polarization was completed. *p < 0.05, **p < 0.01, ***p < 0.001 (one-way RM ANOVA, Bonferroni’s test). Data show the mean ± SEM (n = 8 samples per group)

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