Inositol 1,4,5-trisphosphate receptor type 1 autoantibodies in paraneoplastic and non-paraneoplastic peripheral neuropathy

Table 1 Cerebrospinal fluid findings in patient 1

	d6	d24
Total protein	1571 mg/day	225 mg/day
CSF cell count	Normal	Normal
QAlb	34	48
Blood-CSF barrier dysfunction	Yes^a	Yes^a
Albuminocytologic dissociation	Yes	Yes
CSF lactate	Normal	Normal
CSF glucose	Normal	Normal
OCBs	Mirror pattern^b	Mirror pattern^b
QIgG	Normal	Normal
QIgA	Normal	Normal
QIgM	Normal	Normal
MRZ reaction	Negative	N.d.

No antibodies to Borrelia burgdorferi, Treponema pallidum and Mycobacterium tuberculosis were detected in CSF and serum. CSF-PCR for EBV, HSV-1, HSV-2 and VZV was negative as well
QAlb CSF/serum Alb ratio, QIgG CSF/serum IgG ratio, QIgA CSF/serum IgA ratio, QIgM CSF/serum IgM ratio, MRZ reaction measles, rubella, zoster reaction [61–63], N.d. not done
^aAs indicated by an elevated CSF/serum albumin ratio
^bIndicates systemic immune activation

ISSN: 1742-2094