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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice

Fig. 6

The effects of Sino on the activation of astrocytes and the expression of astrocytic DRD2, CRYAB, and p-STAT3 after OGD induction in vitro. a The morphology changes of astrocytes labeled with GFAP. b Multi-immunofluorescence staining for CRYAB, DRD2, and p-STAT3 in astrocytes after OGD induction. Scale bar = 20 μm (a, b). c–g Western blots and quantitative analysis of GFAP, DRD2, p-STAT3, and CRYAB expression. Data are expressed as mean ± SEM (n = 5). *p < 0.05 and **p < 0.01 vs. sham group; # p < 0.05 and ## p < 0.01 vs. the indicated groups

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