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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction

Fig. 7

Anti-inflammatory effects of DFO on microglia cells in vitro. a Image of western blot protein bands for CD68 and BDNF in microglia cells. b, c Quantification of CD68 and BDNF protein levels. d Image of western blot protein bands for gp91phox and p38 in microglia cells. e, f Quantification of gp91phox and p38 protein levels. g-i Pro-inflammatory cytokines in microglia cells culture medium. DFO exerted anti-inflammatory effects on BV2 cells. n = 6/group except for p38MAPK (n = 4/group), *P < 0.05, **P < 0.01. Data are expressed as mean ± SD. DFO deferoxamine, LPS lipopolysaccharide, BDNF brain-derived neurotropic factor

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Journal of Neuroinflammation

ISSN: 1742-2094