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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: IL-10 plays an important role in the control of inflammation but not in the bacterial burden in S. epidermidis CNS catheter infection

Fig. 6

IL-10 KO mice had significantly greater production of pro-inflammatory mediators following infection despite similar bacterial burdens to wild-type mice (ad). This may explain the greater weight loss observed in these mice and suggests that IL-10 is playing a significant role in regulating the immune response to CNS catheter infection. Results were normalized to the amount of total protein recovered to account for the differences in tissue sampling size. *p < 0.05

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