Fig. 5
From: Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ
Expression of C3 in C/EBPβ wild type and knockout mice. Mice were injected with KA in the right hemisphere, sacrificed 72 h later. a Immunohistochemistry analysis of coronal brain sections using an specific anti-C3 antibody showing the CA3, CA1, and DG fields of the hippocampus. No induction in the expression of C3 was observed in C/EBPβ knockout mice after KA injection, compared with their wild type littermate controls. Scale bar, 50 μm. Inset scale bar, 25 μm. b RT-PCR analysis of C3 mRNA content in the hippocampus of adult C/EBPβ+/+ and C/EBPβ−/− mice treated or not with KA. The graphic shows the mean of three different experiments