Fig. 4

Retinal inflammatory response to intravitreal AQP4-IgG. a H&E staining, and Iba1 and CD45 immunofluorescence (with DAPI counterstain), in posterior retinas at 5 days after intravitreal injection of 40 μg AQP4-IgG (or control-IgG). White arrowheads indicate CD45⁺ cells. b Iba1⁺ cells per mm² of full-thickness retina (mean ± S.E.M, 2 rats, 4 eyes per condition, *p < 0.05, **p < 0.01)