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Table 4 TNF-α modulated expression of genes encoding TJ proteins in BMECs and SCMECs

From: Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells

   Basal TNF-α
   BMEC vs SCMEC BMEC SCMEC
Gene Probe 12 h 24 h 48 h 12 h 24 h 48 h
Ocln (a) A_43_P12552 1.7 0.7 0.5 0.5 0.5 0.6 0.9
Ocln (b) A_44_P1007729 1.7 0.8 0.5 0.7 0.5 0.7 1.0
Cldn5 A_43_P15791 0.8 0.5 0.5 0.4 0.6 0.4 0.4
  1. Ratio of the values in BMECs versus SCMECs and in TNF-α treated cultures after 12, 24, and 48 h versus non-treated cultures were filtered for FC ≥1.45 (in bold) or FC ≤0.69 (in bold and in italic)