Journal of Neuroinflammation

Table 4 TNF-α modulated expression of genes encoding TJ proteins in BMECs and SCMECs

From: Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells

		Basal	TNF-α
		BMEC vs SCMEC	BMEC			SCMEC
Gene	Probe	BMEC vs SCMEC	12 h	24 h	48 h	12 h	24 h	48 h
Ocln (a)	A_43_P12552	1.7	0.7	*0.5*	*0.5*	*0.5*	*0.6*	0.9
Ocln (b)	A_44_P1007729	1.7	0.8	*0.5*	0.7	*0.5*	0.7	1.0
Cldn5	A_43_P15791	0.8	*0.5*	*0.5*	*0.4*	*0.6*	*0.4*	*0.4*

Ratio of the values in BMECs versus SCMECs and in TNF-α treated cultures after 12, 24, and 48 h versus non-treated cultures were filtered for FC ≥1.45 (in bold) or FC ≤0.69 (in bold and in italic)

Back to article page

ISSN: 1742-2094

Contact us

Submission enquiries: journalsubmissions@springernature.com