|
A
| |
Basal
|
TNF-α
|
|---|
| | |
BMEC vs SCMEC
|
BMEC
|
SCMEC
|
|---|
|
Gene
|
Probe
|
12 h
|
24 h
|
48 h
|
12 h
|
24 h
|
48 h
|
|---|
|
Mmp3
|
A_44_P318318
|
0.4
|
34.9
|
9.1
|
3.1
|
7.1
|
7.0
|
5.1
|
|
Mmp12
|
A_44_P555271
|
0.2
|
33.6
|
25.6
|
7.6
|
6.6
|
6.9
|
6.5
|
|
Mmp13
|
A_42_P606126
|
0.2
|
31.4
|
8.8
|
2.4
|
5.7
|
2.9
|
3.1
|
|
Mmp10
|
A_44_P404861
|
0.2
|
16.5
|
8.8
|
10.0
|
6.9
|
8.3
|
9.7
|
|
Cd69
|
A_43_P16166
|
0.5
|
14.7
|
11.6
|
3.2
|
8.4
|
6.7
|
4.8
|
|
Ubd
|
A_42_P602724
|
0.5
|
14.6
|
10.1
|
8.7
|
4.2
|
7.4
|
5.0
|
|
Ccl7
|
A_44_P391296
|
0.3
|
13.6
|
6.2
|
2.8
|
5.5
|
5.0
|
4.5
|
|
Ass1
|
A_44_P391296
|
1.6
|
13.3
|
14.5
|
5.2
|
7.9
|
9.2
|
7.4
|
|
Ptgs2
|
A_44_P472989
|
1.0
|
12.5
|
10.7
|
2.9
|
5.2
|
6.5
|
3.6
|
|
Mmp9
|
A_42_P606126
|
0.3
|
12.1
|
22.2
|
22.6
|
6.4
|
5.2
|
7.5
|
|
B
| |
Basal
|
TNF-α
|
| | |
BMEC vs SCMEC
|
SCMEC
|
BMEC
|
|
Gene
|
Probe
|
12 h
|
24 h
|
48 h
|
12 h
|
24 h
|
48 h
|
|
Mmp9
|
A_44_P501112
|
0.5
|
10.2
|
7.9
|
9.9
|
11.7
|
20.6
|
17.6
|
|
Cd69
|
A_43_P16166
|
0.5
|
8.4
|
6.7
|
4.8
|
14.7
|
11.6
|
3.2
|
|
Ass1
|
A_44_P391296
|
1.6
|
7.9
|
9.2
|
7.4
|
13.3
|
14.5
|
5.2
|
|
Ptges
|
A_43_P12079
|
1.1
|
7.3
|
5.9
|
4.9
|
7.2
|
6.1
|
4.3
|
|
Mmp3
|
A_44_P318318
|
0.4
|
7.1
|
7.0
|
5.1
|
34.9
|
9.1
|
3.1
|
|
Mmp10
|
A_44_P404861
|
0.2
|
6.9
|
8.3
|
9.7
|
16.5
|
8.8
|
10.0
|
|
Mmp12
|
A_44_P555271
|
0.2
|
6.6
|
6.9
|
6.5
|
33.6
|
25.6
|
7.6
|
|
Ccl5
|
A_44_P304323
|
0.2
|
6.5
|
7.7
|
8.0
|
7.8
|
11.0
|
16.7
|
|
Cxcl3
|
A_44_P363116
|
0.5
|
6.1
|
5.0
|
3.9
|
9.8
|
7.5
|
2.7
|
|
Cxcl11
|
A_44_P175495
|
0.4
|
5.9
|
8.9
|
6.4
|
8.6
|
7.8
|
5.6
|
- Ratio of the values in BMECs versus SCMECs and in TNF-α treated cultures after 12, 24, and 48 h versus non-treated cultures were filtered for FC ≥1.45 (in bold) or FC ≤0.69 (in bold and in italic)
