Fig. 6

Brain Ly6C^lo Mo/MΦ develop independently of circulating Ly6C^lo monocytes after MCAo. a Blood flow cytometry analysis shows absence of Ly6C^lo monocytes, identified by expression of CD115 and low Ly6G expression, in NR4A1^−/− BM chimeric mice (n = 6 mice/group). *p < 0.05 vs. irradiated WT mice (WT → WT). b Brain flow cytometry analysis from NR4A1^−/− chimeric mice shows an increase of infiltrating Ly6C^lo Mo/MΦ, identified by high expression of CD45 and CD11b and low expression of Ly6G (CD45^hiCD11b⁺Ly6G⁻), 14 days after MCAo compared to 3 days after MCAo. *p < 0.05 vs. 3 days