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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response

Fig. 2

miR-155 inhibition results in long-term changes in cytokine profiles. Protein expression of 20 major pro- and anti-inflammatory cytokines was measured using Mouse Cytokine Magnetic 20-Plex Panel Kit (Life Tech/Invitrogen), at 48 h and 7, 14, and 21 days after dMCAO. Samples were collected from lesioned (thick red and blue plots) and unlesioned hemispheres (light red and blue plots) of mice from control and inhibitor groups, respectively. Sham group (dark grey plots) did not receive any injections. dMCAO and sham-operated animals were used to measure cytokine expressions at 48 h after dMCAO (orange diamond and grey triangle). N = 6 mice per group/per time point. Two-way ANOVA followed by Tukey’s multiple comparison test; *p < 0.05, **p < 0.01. Error bars: SEM

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