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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit

Fig. 4

ELISA quantification of cytokine response to LPS stimulation over time. a Vascular chamber and brain chamber both elevate GM-CSF at 6 h but not 24 h (p = .02, p = .016, N = 7). b Vascular chamber decreases IL-17A at 6 and 24 h (p = .05, p = .05, N = 7), whereas brain chamber increases IL-17A at 6 and 24 h (p = .001, p = .002, N = 7). c Vascular chamber and brain chamber show similar time-dependent elevations in TNF-α (p = .01, p = .01, N = 7)

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