Fig. 10

IGFBP-3 level is increased in ischemic hemisphere at 5 days post MCAo. IGFBP-3 levels were measured from cortex and striatum (a), serum (b), liver (c), and spleen (d) samples collected at 5 days post stroke. IGFBP3 levels are significantly elevated in the ischemic hemisphere compared to the non-ischemic hemisphere. NaB did not affect IGFBP3 expression in any of these tissue. All graphs represent mean ± S.E.M. n = 6 in each group. ***p < 0.001 main effect of hemisphere. Two-way ANOVA (a) and unpaired t test (b–d). ICS ischemic cortex and striatum, NICS non-ischemic cortex and striatum