Fig. 1
From: miR-15a/16 reduces retinal leukostasis through decreased pro-inflammatory signaling
Decrease of miR-15a expression in high glucose conditions, and transfection-induced fold changes. a Fold change of miR-15a expression is shown. After 3 days of REC culture in high glucose (25 mM) medium, miR-15a expression was reduced (0.4-fold reduction) compared to that in normal glucose (NG; 5 mM) group. b Fold changes of miR-15a/16 after transfection in REC. REC were transfected with mimics (30 nM of final concentration) of miR-15a and/or miR-16 in high glucose conditions. Approximately 84- and 114-fold increases of miR-15a levels were detected following transfection with miR-15a and miR-15a/16 mimics, respectively, compared to HG control. *p < 0.05 versus HG, N = 3; data are mean ± SEM