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Table 3 Summary of statistical tests of associations between changes in MMSE for 52 weeks and changes in each biomarker for 52 among patients treated with placebo (N = 19) or resveratrol (N = 19)

From: Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

Association between changes in MMSE and changes in biomarkers
CSF p value Plasma p value
Aβ40 0.8367 MMP-9 0.1061
Aβ42 0.2180 MMP-3 0.1358
pTau 181 0.4521 MMP-2 0.4234
tTau 0.6607 MMP-10 0.6379
MMP-9 0.1061 MMP-12 0.9992
MMP-3 0.1358 MMP-13 0.5432
MMP-2 0.4234 MMP-1 0.9490
MMP-10 0.6379 FGF-2 0.5382
FGF-2 0.5382 G-CSF 0.3103
TGFα 0.1270 MDC 0.7157
G-CSF 0.3103 PDGF-AA 0.2266
MCP-3 0.8066 PDGF-AB/BB 0.8598
MDC 0.7157 IL-8 0.0705
PDGF-AA 0.2266 EGF 0.3491
IL-4 0.7163 Eotaxin 0.2782
PDGF-AB/BB 0.8598 GM-CSF 0.9380
IL-8 0.0705 Fractalkine 0.4894
Flt-3L 0.2061 IFNα2 0.9855
Fractalkine 0.4894 IFNy 0.3895
IFNα2 0.9855 GRO 0.2955
IL-15 0.8288 IL-12P40 0.7747
IL-7 0.8204 IL-12P70 0.8371
IP-10 0.2102 sCD40L 0.3075
MCP-1 0.2516 IL-17A 0.8985
MIP-1b 0.5144 IL-1RA 0.5109
   IL-2 0.6367
   IP-10 0.2102
   MCP-1 0.2516
   MIP-1a 0.6162
   MIP-1b 0.5144
   RANTES 0.4541
   TNFα 0.2814
  1. Indicated in bold typeface represents significant associations (at level 0.05) after the Benjamini–Hochberg correction