Table 3 Summary of statistical tests of associations between changes in MMSE for 52 weeks and changes in each biomarker for 52 among patients treated with placebo (N = 19) or resveratrol (N = 19)
From: Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease
Association between changes in MMSE and changes in biomarkers | |||
|---|---|---|---|
CSF | p value | Plasma | p value |
Aβ40 | 0.8367 | MMP-9 | 0.1061 |
Aβ42 | 0.2180 | MMP-3 | 0.1358 |
pTau 181 | 0.4521 | MMP-2 | 0.4234 |
tTau | 0.6607 | MMP-10 | 0.6379 |
MMP-9 | 0.1061 | MMP-12 | 0.9992 |
MMP-3 | 0.1358 | MMP-13 | 0.5432 |
MMP-2 | 0.4234 | MMP-1 | 0.9490 |
MMP-10 | 0.6379 | FGF-2 | 0.5382 |
FGF-2 | 0.5382 | G-CSF | 0.3103 |
TGFα | 0.1270 | MDC | 0.7157 |
G-CSF | 0.3103 | PDGF-AA | 0.2266 |
MCP-3 | 0.8066 | PDGF-AB/BB | 0.8598 |
MDC | 0.7157 | IL-8 | 0.0705 |
PDGF-AA | 0.2266 | EGF | 0.3491 |
IL-4 | 0.7163 | Eotaxin | 0.2782 |
PDGF-AB/BB | 0.8598 | GM-CSF | 0.9380 |
IL-8 | 0.0705 | Fractalkine | 0.4894 |
Flt-3L | 0.2061 | IFNα2 | 0.9855 |
Fractalkine | 0.4894 | IFNy | 0.3895 |
IFNα2 | 0.9855 | GRO | 0.2955 |
IL-15 | 0.8288 | IL-12P40 | 0.7747 |
IL-7 | 0.8204 | IL-12P70 | 0.8371 |
IP-10 | 0.2102 | sCD40L | 0.3075 |
MCP-1 | 0.2516 | IL-17A | 0.8985 |
MIP-1b | 0.5144 | IL-1RA | 0.5109 |
IL-2 | 0.6367 | ||
IP-10 | 0.2102 | ||
MCP-1 | 0.2516 | ||
MIP-1a | 0.6162 | ||
MIP-1b | 0.5144 | ||
RANTES | 0.4541 | ||
TNFα | 0.2814 | ||