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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: WWL70 attenuates PGE2 production derived from 2-arachidonoylglycerol in microglia by ABHD6-independent mechanism

Fig. 10

WWL70 inhibited PGE2 in primary microglia. PGE2 EIA of media from primary microglia. a Cells were treated with LPS for 18 h in the presence or absence of WWL70, KT182, or CB1 or CB2 receptor antagonist. b Microglia were treated with LPS for 18 h before media were replaced with DMEM containing WWL70 (10 μM), KT182 (0.1 μM), AA (10 μM), or 2-AG (10 μM) and incubated for 30 min. The data are represented as mean ± SD (n = 3). Single and triple asterisks denote p < 0.05 and 0.001, respectively

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