Fig. 10
WWL70 inhibited PGE2 in primary microglia. PGE2 EIA of media from primary microglia. a Cells were treated with LPS for 18 h in the presence or absence of WWL70, KT182, or CB1 or CB2 receptor antagonist. b Microglia were treated with LPS for 18 h before media were replaced with DMEM containing WWL70 (10 μM), KT182 (0.1 μM), AA (10 μM), or 2-AG (10 μM) and incubated for 30 min. The data are represented as mean ± SD (n = 3). Single and triple asterisks denote p < 0.05 and 0.001, respectively