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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset

Fig. 1

IgG and cytokine concentrations in the CSF. IgG Loc expressed in mg/dL (a), CSF CXCL13 and IL-21 concentrations (pg/mL; b, c), and BAFF Index values (d) in HC and CIS/eRRMS with (IgGOB+) or without (IgGOB−) intrathecal synthesis of IgG oligoclonal bands. IgGOB+ patients had increased CXCL13, normal IL-21, and decreased BAFF Index compared to HC and IgGOB− patients. Only significant comparison is indicated. Abbreviations: HC healthy controls, CIS/eRRMS CIS suggestive of MS or early RRMS, LP lumbar puncture, n.a. not applicable, CSF cerebrospinal fluid, S serum. IgGOB+: patients with IgG oligoclonal bands in the CSF; IgGOB−: patients without IgG oligoclonal bands in the CSF

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Journal of Neuroinflammation

ISSN: 1742-2094