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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Absence of system xc on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

Fig. 1

Increased xCT and iNOS protein expression in the NAWM of MS patients. a Real-time PCR revealed no significant difference in xCT mRNA levels between the NAWM of MS patients and corresponding tissue of control subjects when normalized to GAPDH as internal control. xCT (b) and iNOS (c) protein levels are significantly increased in NAWM of MS patients compared to controls as measured using semi-quantitative Western blotting. Normalization was performed by using total protein staining. Individual expression levels are presented as scatter dot plot and horizontal lines represent mean ± SEM (Mann-Whitney U test, *p < 0.05). Controls (n = 5), MS patients (n = 8). Protein bands for xCT (b) and iNOS (c) of a representative sample of control and MS patients are shown in the inset

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