Fig. 6

Immune cell infiltration into the CNS of irradiated mice transplanted with BM originating from xCT^+/+ or xCT^−/− mice is not different between the two groups after EAE induction. Proportion of immune cells relative to the total amount of isolated cells (a) and the proportion of CD4⁺, CD11b⁺, CD4⁺IL-17⁺, CD4⁺IFN-γ⁺, and CD4⁺FoxP3⁺ cells within the immune cell population (b) in the CNS after EAE induction in mice that are expressing (xCT^+/+ BM mice) or lacking xCT in their immune cells (xCT^−/− BM mice). Data shown are means ± SEM; Mann-Whitney U test