Fig. 1

Statistical maps depicting brain areas in which the gray matter intensity covaried with (a) four target seeds, (b) comparisons of seed volumes, and (c) separate structural covariance network in patients with Alzheimer’s disease with interleukin-1 beta genotypes (C carrier n = 108, T homozygotes n = 27). There was no significant difference in seed volume between the genotype groups (p > 0.05). Z-statistic maps (p < 0.05, corrected with a false discovery rate with extended cluster voxels >100) are displayed on a standard brain render