Table 1 Demographical characteristics and neuropsychiatric tests in the interleukin-1 beta C-carrier and TT-carriers in 135 cases
Group | C-carrier (n = 108) | TT-carriers (n = 27) | p value |
|---|---|---|---|
Age | 71.7(14.2) | 72.6(7.4) | 0.77 |
Education (year) | 6.9(4.7) | 9.3(4.8) | 0.02 |
Apolipoprotein E4 carrier (positive case, %) | 42.6% | 48.1% | 0.67 |
Sex (male/female) | 56/52 | 14/13 | 1 |
Mini-Mental State Examination | 20.2(6.2) | 20.6(7.7) | 0.82 |
CASI total scores | 67.8(20.2) | 68.3(25.1) | 0.89 |
CASI executive function test scores | 25.3(7.9) | 25.2(10.1) | 0.97 |
CASI subdomains | |||
Short term memory | 5.5(3.8) | 5.4(3.8) | 0.90 |
Orientation | 12.8(5.1) | 12.9(6.0) | 0.88 |
Long term memory | 8.3(2.4) | 8.4(2.7) | 0.90 |
Language | 8.2(2.1) | 8.1(2.8) | 0.83 |
Drawing | 7.8(2.8) | 8.4(2.6) | 0.37 |
Attention | 6.3(1.4) | 6.3(1.6) | 0.98 |
Verbal fluency | 5.2(2.5) | 5.3(3.7) | 0.86 |
Abstract thinking | 8.2(2.8) | 7.9(3.2) | 0.64 |
Mental manipulation | 5.6(3.2) | 5.7(3.4) | 0.92 |
Cerebrovascular risk biomarkers | |||
High sensitive C reactive protein (mg/L) | 2.8(4.9) | 2.4(5.2) | 0.68 |
Homocysteine (umol/L) | 12.9(4.3) | 11.5(4.7) | 0.14 |
Hemoglobin-A1C (%) | 6.1(1.0) | 6.2(1.7) | 0.74 |
Creatinine (mg/dl) | 0.9(0.4) | 0.9(0.2) | 0.52 |
High-density lipoprotein (mg/dl) | 57.1(17.0) | 61.0(16.6) | 0.29 |
Low-density lipoprotein (mg/dl) | 106.2(38.1) | 97.4(28.6) | 0.27 |
Total cholesterol (mg/dl) | 188.5(40.8) | 180.6(36.0) | 0.36 |
Triglyceride (mg/dl) | 120.7(62.0) | 110.7(55.0) | 0.44 |
Vitamin B12 (pg/dl) | 589.1 (315.7) | 687.2(428.1) | 0.19 |
Folate (ng/dl) | 12.0(5.6) | 12.8(5.4) | 0.52 |