Fig. 6

Effect of rapamycin on microglia activation after 2 days of QA administration (n = 3–4 animals/group). Rapamycin was injected 15 min before QA injection into the striatum, and after 2 days, Iba-1 staining was performed. a–e Representative images of the staining with anti-Iba-1 antibody in the right striatum at 20× (ipsilateral). f Quantitative analysis of the cell area divided by the number of the cells. Results are expressed as mean ± SEM. *p < 0.05 as compared with vehicle + PBS (one-way ANOVA followed by Newman-Keuls test)