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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis

Fig. 3

HIV induces multiple elements for activation of the C3 promoter in HFA. HFA were treated with pharmacological agents as indicated prior to exposure to medium, HIV, or mock virus and luciferase construction transfection. a, b Activity of the C3 promoter was assayed by luciferase expression, data are expressed as RLU. c Data are expressed as fold change relative to mock-infected cells. The differences in values between the untreated mock-infected (a, c) or untreated medium (b) and the other groups were tested by one-way ANOVA and Dunnett’s post hoc analysis with asterisk indicating p < 0.05. Statistical values are provided in Additional file 1: Table S1

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