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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis

Fig. 4

C3 induction by HIV in HFA requires activation of NF-κB. HFA were treated as indicated and a assayed for translocation of NF-κB into the nucleus by ELISA or b assayed for C3 promoter activity in the presence of adenovirus control vector or vector of dominant negative I-κBmt32. The differences in between untreated mock-infected and the other experimental groups were tested by one-way ANOVA and Dunnett’s post hoc analysis with asterisk indicating p < 0.05. Statistical values are provided in Additional file 1: Table S1

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