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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis

Fig. 6

Elements in the C3 promoter essential for activation of HFA by HIV. HFA were exposed to HIV or mock virus and then transfected with various mutant C3 promoters driving luciferase production. a Truncation mutants in the C3 promoter. b Point mutants in the C3 promoter. The differences in values between the intact C3 promoter and deletion or point mutations (HIV-1) were tested by one-way ANOVA and Dunnett’s post hoc analysis with number sign indicating p < 0.05. Statistical values are provided in Additional file 1: Table S1

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Journal of Neuroinflammation

ISSN: 1742-2094