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Table 1 Decreased frequencies of TGF-β1-expressing B cells upon in vitro polyclonal stimulation

From: Activation of human B cells negatively regulates TGF-β1 production

 

% IL-10

% TGF-β1

% LAP (TGF-β1)

CD19+ CD27

CD19+ CD27+

CD19+ CD27

CD19+ CD27+

CD19+ CD27

CD19+ CD27+

Unstimulated

0.15 ± 0.09

0.17 ± 0.11

3.54 ± 0.69

4.15 ± 0.56

5.43 ± 1.11

5.40 ± 1.37

[0.00–0.56]

[0.00–0.74]

[1.80–7.07]

[2.82–6.93]

[1.74–9.92]

[1.58–11.12]

Stimulated

0.81 ± 0.28

4.28 ± 1.02

1.20 ± 0.12

1.86 ± 0.40

3.74 ± 1.19

3.86 ± 1.18

[0.00–1.95]

[1.75–9.38]

[0.82–1.57]

[0.82–3.28]

[0.84–9.05]

[1.03–8.53]

  1. Values indicate frequencies (mean ± SEM) with range (number in parentheses) of cytokine-producing B cells in both CD19+CD27 and CD19+CD27+ B cell subpopulations (n = 6). Frequencies were normalized to the isotype control