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Table 1 Decreased frequencies of TGF-β1-expressing B cells upon in vitro polyclonal stimulation

From: Activation of human B cells negatively regulates TGF-β1 production

  % IL-10 % TGF-β1 % LAP (TGF-β1)
CD19+ CD27 CD19+ CD27+ CD19+ CD27 CD19+ CD27+ CD19+ CD27 CD19+ CD27+
Unstimulated 0.15 ± 0.09 0.17 ± 0.11 3.54 ± 0.69 4.15 ± 0.56 5.43 ± 1.11 5.40 ± 1.37
[0.00–0.56] [0.00–0.74] [1.80–7.07] [2.82–6.93] [1.74–9.92] [1.58–11.12]
Stimulated 0.81 ± 0.28 4.28 ± 1.02 1.20 ± 0.12 1.86 ± 0.40 3.74 ± 1.19 3.86 ± 1.18
[0.00–1.95] [1.75–9.38] [0.82–1.57] [0.82–3.28] [0.84–9.05] [1.03–8.53]
  1. Values indicate frequencies (mean ± SEM) with range (number in parentheses) of cytokine-producing B cells in both CD19+CD27 and CD19+CD27+ B cell subpopulations (n = 6). Frequencies were normalized to the isotype control