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Table 2 Activation of human B cells restrains TGF-β1 production

From: Activation of human B cells negatively regulates TGF-β1 production

  Normalized IL-10 MFI Normalized TGF-β1 MFI Normalized LAP (TGF-β1) MFI
CD19+ CD27 CD19+ CD27+ CD19+ CD27 CD19+ CD27+ CD19+ CD27 CD19+ CD27+
Unstimulated 0.67 ± 0.13 0.89 ± 0.11 0.30 ± 0.02 0.34 ± 0.02 3.06 ± 0.36 2.59 ± 0.40
[0.14–1.10] [0.55–1.37] [0.25–0.38] [0.29–0.44] [2.18–4.75] [1.63–4.32]
Stimulated 1.06 ± 0.10 1.70 ± 0.15 0.15 ± 0.01 0.18 ± 0.02 2.38 ± 0.22 2.27 ± 0.31
[0.70–1.42] [1.25–2.41] [0.11–0.17] [0.13–0.22] [1.78–3.35] [1.52–3.68]
  1. Values indicate quantification (mean ± SEM) with range (number in parentheses) of cytokine staining in both CD19+CD27 and CD19+CD27+ B cells (n = 6). Geometric mean fluorescence intensities (MFI) were normalized to the isotype control