Table 2 Demographics of alcoholics and control subjects from New South Wales Brain Tissue Bank
From: Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7
DSM V alcohol classification | Age | PMI | Brain pH | RIN | Lifetime alcohol (kg) | Cause of death | Agonal state/mode of death |
|---|---|---|---|---|---|---|---|
Control | 24 | 43 | 6.27 | 6.2 | 15 | Arrhythmia | Rapid |
Control | 40 | 27 | 6.79 | 7.4 | 47 | Pulmonary embolus | Intermediate |
Control | 44 | 50 | 6.6 | 7.1 | 28 | IHD | Rapid |
Control | 46 | 29 | 6.12 | 4.4 | 115 | MI | Intermediate |
Control | 48 | 24 | 6.73 | 6.9 | 17 | IHD | Rapid |
Control | 50 | 30 | 6.37 | 7.5 | 0 | IHD | Rapid |
Control | 50 | 40 | 6.87 | 8.6 | 18 | Hemopericardium | Rapid |
Control | 53 | 16 | 6.84 | 7.9 | 102 | Cardiomyopathy | Rapid |
Control | 60 | 28 | 6.8 | 8 | 0 | IHD | Rapid |
Control | 62 | 46 | 6.95 | 8.8 | 5 | IHD | Rapid |
Mean ± SEM | 48 ± 3 | 33 ± 3 | 6.56 ± 0.1 | 7.28 ± 1 | 35 ± 13 | ||
AUD, mild | 25 | 43.5 | 6.7 | 6.9 | 552 | CO and EtOH | Intermediate |
AUD, moderate | 42 | 41 | 6.5 | 8 | 1472 | Bromoxynil/EtOH | Intermediate |
AUD, remission | 44 | 15 | 6.48 | 7.9 | 639 | IHD | Rapid |
AUD, severe | 45 | 18.5 | 6.57 | 7.9 | 1799 | Drowning | Intermediate |
AUD, severe | 49 | 44 | 6.41 | 6.4 | 1012 | IHD | Rapid |
AUD, severe | 49 | 16 | 6.19 | 6.2 | 613 | MI | Rapid |
AUD, moderate | 50 | 17 | 6.3 | 7.0 | 2453 | IHD | Rapid |
AUD, severe | 50 | 34.5 | 6.93 | 7.3 | 5212 | Acute bronchitis | Intermediate |
AUD, severe | 61 | 59 | 6.57 | 6.1 | 8052 | Myocarditis | Intermediate |
AUD, severe | 61 | 23.5 | 6.92 | 8.3 | 5621 | IHD | Rapid |
Mean ± SEM | 48 ± 3 | 31 ± 5 | 6.63 ± 0.1 | 7.2 ± 1 | 2743 ± 829 |