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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin

Fig. 1

Analysis of energy homeostatic and metabolic parameters. EMD (n = 12) and control (n = 10) mice were evaluated for 20 weeks. a Weekly body weight, measured along 20 weeks, was significantly increased in EMD mice compared to wt mice. b Adiposity index was significantly increased in EMD mice compared to wt mice. c Daily food intake was increased in EMD mice compared to wt mice. d Relative weight of liver was reduced in EMD mice compared to wt mice. (e–g) e Plasma levels of leptin, f insulin, and g triglycerides were significantly increased in EMD mice compared to wt mice. h Glucose tolerance was assessed over 120 min in EMD mice compared to wt mice. i The area under curve (AUC) was calculated for respective groups and used for statistical analysis. TG triglycerides. Data are presented as mean ± SEM. *P < 0.05, **P < 0.01; Student’s t test.

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