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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

Fig. 2

Collagen is degraded by neutrophils stimulated with M.tb in an MMP-9 dependent manner. a Confocal microscopy of Type IV DQ collagen coated slides demonstrating collagen degradation in the presence of M.tb stimulation. DQ collagen fluorescence increases after degradation. b Type IV collagenase activity is inhibited by MMP-9 neutralizing antibody. Bars represent mean ± s.d and represent two independent experiment performed in triplicate. **P < 0.01

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