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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons

Fig. 8

Aβo enhance TLR4 expression in aged cultures of rat hippocampal neurons but not in young cultures. a Representative fluorescence images of TLR4 immunofluorescence in 8, 15, and 22 DIV cultured hippocampal neurons. Vehicle refers to images taken from similar cultures in the absence of Aβo treatment. Scale bar is 10 μm and applies to all frames. b Quantitative analysis of immunofluorescence (Optical Density in arbitrary units) for TLR4. Bars represent mean ± SEM (n = 25–75 cells from three independent cultures). *p < 0.05 vs 8 DIV; # p < 0.05 vs vehicle

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