Fig. 1From: Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIaGenetic deficiency and pharmacologic inhibition of factor XIIa provides protection from tissue damage. Lesion volumetry shows less necrotic brain tissue in FXII−/− mice and mice treated with rHA-Infestin-4 in comparison with control groups after 1 day (d1) and 3 days (d3), respectively (n = 8, **P < 0.01, *P < 0.05, unpaired, two-tailed Student’s t test)Back to article page