Fig. 5

Cytokine production and macular atrophy. CCL2, IL-8 and VEGF levels in PBMC supernatants from healthy controls and nAMD patients without and with macular atrophy (MA) under non-stimulated condition (a), following LPS treatment (b) and under hypoxic condition (c). Controls n = 28, MA (−) n = 17, MA (+) n = 35; mean + SEM; #P < 0.05, ##P < 0.01 in univariate analysis using one-way ANOVA. *P < 0.05, **P < 0.01 in multivariate analysis using multinomial logistic regression