Fig. 4

LPS effects on astrocytosis in the striatum of WT and PTN-Tg mice. Photomicrographs are from GFAP-immunostained striatal sections of saline + saline (Sal)- or saline + LPS (LPS)-treated animals (n = 4–5/group). The graph represents quantification of data obtained from the counts of GFAP-positive cells in the striatum. Scale bar = 200 μm. SAL saline, LPS lipopolysaccharide, WT wild-type mice, PTN-Tg mice with transgenic pleiotrophin overexpression in the brain, GFAP glial fibrillary acidic protein