Responses in 3xTg-AD mice to infection with the nematode parasite T. muris.
a 6-month-old mice were infected with 40 viable eggs of the E strain of T. muris (low dose) and sacrificed at 35 days PI. MLNs from T. muris-infected mice were plated 1 × 106 cells/well of a 96-well plate and stimulated with E/S antigen (50 μg/ml) for 48 h; cytokine and chemokine levels were measured by CBA. b
T. muris worm burden was enumerated. Scale bars show 100 μm. *P < 0.05; **P ≤ 0.01; ***P ≤ 0.001. All data are shown as mean ± SEM